Ethylenediamine → HCID 13715405, compound

HRID 1607124Notes

Reaction equation

HRID 1607124 reaction equation
[NH2:1][CH2:2][CH2:3][NH2:4].[C:5]1(=[O:10])[O:9][CH:7]([CH3:8])[CH2:6]1>O>[OH:9][CH:7]([CH3:8])[CH2:6][C:5]([NH:1][CH2:2][CH2:3][NH2:4])=[O:10]

Participants

4

Reactant 2

HCID 3301EthylenediamineHCID 18303beta-BUTYROLACTONE

Product 1

HCID 13715405HCID 13715405, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

192 ml. 1,2-diaminoethane are mixed with 60 ml. water and, with stirring and gentle cooling at 20°-30° C., 74 ml. β-butyrolactone are added dropwise thereto. After 4 days, the reaction mixture is distilled off in a vacuum and the crystal slurry obtained is dried over sulphuric acid in a desiccator. There are obtained 122.4 g. (93% of theory) of the desired base; m.p. 71°-73° C.

Workup

  1. temperaturegentle cooling at 20°-30° C.
  2. distillationthe reaction mixture is distilled off in a vacuum
  3. customthe crystal slurry obtained
  4. dry with materialis dried over sulphuric acid in a desiccator
  5. customThere are obtained 122.4 g

Sources & evidence

ORD record
ord-61a5e280000d46e3a80cb0f7f0b61087
Source dataset
uspto-grants-1989_09
Patent number
US04863949

Reaction notes

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