Pyridine → HCID 19818641, compound

Participants

Reaction Steps

A solution of 1.9 ml of chloro-oxalic acid methyl ester in 10 ml of methylene chloride is added dropwise in the course of 10 minutes to a solution of 2.5 g of 3-aminoanisole and 1.5 ml of pyridine in 40 ml of methylene chloride. After stirring for 3 hours at room temperature the mixture is poured onto water and extracted with methylene chloride. The extracts are dried over sodium sulphate, concentrated by evaporation and crystallised from ether/hexane. N-(3-methoxyphenyl)-oxamic acid methyl ester is obtained.

Provenance & Evidence