Water → HCID 13280856, compound

HRID 1607165Notes

Reaction equation

HRID 1607165 reaction equation
B(Br)(Br)Br.[CH3:5][O:6][C:7](=[O:19])[C:8]([NH:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([O:17]C)[CH:12]=1)=[O:9].O>C(Cl)Cl>[CH3:5][O:6][C:7](=[O:19])[C:8]([NH:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([OH:17])[CH:12]=1)=[O:9]

Participants

5

Reactant 3

HCID 962WaterHCID 25134Boron tribromideHCID 19818641HCID 19818641, compound

Product 1

HCID 13280856HCID 13280856, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

5 g of boron tribromide are added dropwise in the course of 5 minutes to a solution, cooled to -78° C., of 2 g of N-(3-methoxyphenyl)-oxamic acid methyl ester in 20 ml of methylene chloride. The whole is stirred for 5 hours at room temperature, 5 ml of water are added thereto while cooling and the organic phase is separated off. After drying over sodium sulphate and concentration by evaporation, N-(3-hydroxyphenyl)-oxamic acid methyl ester is obtained.

Workup

  1. temperaturewhile cooling
  2. customthe organic phase is separated off
  3. dry with materialAfter drying over sodium sulphate and concentration by evaporation

Sources & evidence

ORD record
ord-55cf09acc48b47659bb060a2e361e457
Source dataset
uspto-grants-1989_09
Patent number
US04863942

Reaction notes

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