HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1607167Generated: October 30, 2026
Trifluoroacetic acid → HCID 178473797, compound
https://huagongshe.com/reaction/1607167
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Phosphorus oxide (P4O10) | HCID 14812 | — |
| Reactant | HCID 14183251 | HCID 14183251 | — |
| Product | HCID 178473797 | HCID 178473797 | 31% |
Reaction Steps
A mixture of 60 g. polyphosphoric acid, 1.6 ml. trifluoroacetic acid, 18 g. phosphorus pentoxide and 4.0 g. (18 mmole) 1-acetyl-5,6-diamino-3,3-dimethylindoline (Example 2b) is stirred for 7 hours at 150°-160° C. The reaction mixture is allowed to cool to 90° C., poured on to ice, left to stand overnight and filtered to give 1.7 g. (31%) of the title compound; m.p. 290°-291° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04863945 |
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| Source dataset | uspto-grants-1989_09 |
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| ORD ID | ord-eb5efc73f74a4e2db9cd7b7831fb62ad |
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| Source note | uspto-grants-1989_09 |
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