HCID 14621075, compound → HCID 14621076, compound
Reaction equation
[NH2:1][C:2]1[C:9]([CH3:10])=[CH:8][C:5]([CH:6]=[O:7])=[C:4]([F:11])[C:3]=1[Br:12].[CH3:13][Mg+].[Br-]>>[NH2:1][C:2]1[C:9]([CH3:10])=[CH:8][C:5]([CH:6]([OH:7])[CH3:13])=[C:4]([F:11])[C:3]=1[Br:12]Participants
3
Procedure
Using the method of Example 19, 4-amino-3-bromo-2-fluoro-5-methylbenzaldehyde is reacted with MeMgBr to afford the title compound.
Sources & evidence
- ORD record
- ord-8e6aa55af84544868ef024eb83df9886
- Source dataset
- uspto-grants-1989_09
- Patent number
- US04863959
Reaction notes
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