反应详情

To an ether solution containing approximately 14 g (55 mmole) of 3-(4-chlorophenyl)-4-carbomethoxy-4-methyl-4,5-dihydro-1H-pyrazole (Example O) was bubbled excess anhydrous hydrogen chloride. The precipitated solid was filtered, washed with ether and dried yielding 15.5 g (53.6 mmole) of 3-(4-chlorophenyl)-4-carbomethoxy-4-methyl-4,5-dihydro-1H-pyrazole hydrochloride. NMR data was consistent with the structure.

1. customwas bubbled excess anhydrous hydrogen chloride
2. filtrationThe precipitated solid was filtered
3. washwashed with ether
4. customdried