HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 3-Methyl-4-acetoxybenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-Methyl-1-benzofuran-4-ol | HCID 11008068 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Methyl-4-acetoxybenzofuran | HCID 14579793 | — |
Reaction Steps
A solution of 3-methyl-4-hydroxybenzofuran (5.0 gm, 34.7 mmoles), acetic anhydride (50 mL) and triethylamine (25 mL) in tetrahydrofuran (150 mL) was stirred at room temperature overnight. The volatiles were removed in vacuo and the residue was purified by chromatography on silica gel. Elution with 15% ethylacetate in hexane yielded 3-methyl-4-acetoxybenzofuran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04863958 |
| Source dataset | uspto-grants-1989_09 |
| ORD ID | ord-69396100fb174d618f6d5b7d7400c5e1 |
| Source note | uspto-grants-1989_09 |