HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfate → 1,2-Dimethyl-1H-imidazole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | Methyl 1,2-dimethyl-1H-imidazole-5-carboxylate | HCID 14344426 | — |
| Product | 1,2-Dimethyl-1H-imidazole-5-carboxylic acid | HCID 23361873 | 67% |
Reaction Steps
In the manner described in Example 1 126 g (1 mol) of 2-methylimidazole-4(5)-carboxylic acid was treated with dimethyl sulfate and the product was converted into its methyl ester for characterization. This gave 103.3 g of methyl 1,2-dimethylimidazole-5-carboxylate, m.p. 38°-40° C., an overall yield of 67%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04864030 |
| Source dataset | uspto-grants-1989_09 |
| ORD ID | ord-eed292a70e304ba7b0b778555e3424ad |
| Source note | uspto-grants-1989_09 |