5-Chloro-2-propyl-[1,8]naphthyridine → N-{3-Fluoro-4-[4-methyl-2-(7-propyl-[1,8]naphthyridin-4-ylamino)-phenylsulfanyl]-phenyl}-acetamide
Reaction equation
[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6]([CH2:12][CH2:13][CH3:14])[n:7][c:8]2[n:9][cH:10][cH:11]1.[NH2:15][c:16]1[c:17]([S:23][c:24]2[c:25]([F:34])[cH:26][c:27]([NH:30][C:31]([CH3:32])=[O:33])[cH:28][cH:29]2)[cH:18][cH:19][c:20]([CH3:22])[cH:21]1>>[c:2]1([NH:15][c:16]2[c:17]([S:23][c:24]3[c:25]([F:34])[cH:26][c:27]([NH:30][C:31]([CH3:32])=[O:33])[cH:28][cH:29]3)[cH:18][cH:19][c:20]([CH3:22])[cH:21]2)[c:3]2[cH:4][cH:5][c:6]([CH2:12][CH2:13][CH3:14])[n:7][c:8]2[n:9][cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-0ee5a758c4194660b7b12b2f92dd4eb9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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