反应详情

温度

65 °C

In 55 ml of methanol, 3.3 g of 2-heptylthio-6-methoxy-5H-1,3,4-thiadiazolo[3,2-a]pyrimidin-5-one was dissolved. A dispersion of 19.4 g of OXONE® suspended in 70 ml of water was added to the methanol solution, and the resulting mixture was warmed to 65° C. and stirred for 1 hour. The residue obtained by the same procedure as in Preparation Example 7 was recrystallized from ethanol and thus 1.8 g of 2-heptanesulfonyl-6-methoxy-5H-1,3,4-thiadiazolo[3,2-a]pyrimidin-5-one was obtained.

1. customThe residue obtained by the same procedure as in Preparation Example 7
2. customwas recrystallized from ethanol