HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus pentachloride → 3-(2,4-Difluorophenoxy)-4-methanesulfonamidobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus pentachloride | HCID 24819 | — |
| Reactant | HCID 10472595 | HCID 10472595 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 3-(2,4-Difluorophenoxy)-4-methanesulfonamidobenzoyl chloride | HCID 10090001 | 110.7% |
Reaction Steps
A mixture of 3-(2,4-difluorophenoxy)-4-methanesulfonamidobenzoic acid (0.6 g) and phosphorus pentachloride (0.4 g) in benzene (6 ml) was warmed, dissolved, and then stirred for 25 minutes at room temperature. The mixture was concentrated under reduced pressure to give a powder of 3-(2,4-difluorophenoxy)-4-methanesulfonamidobenzoyl chloride (0.7 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04866091 |
| Source dataset | uspto-grants-1989_09 |
| ORD ID | ord-3dd48d6f55af4ba1ae859d30f8b704e2 |
| Source note | uspto-grants-1989_09 |