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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 16077Generated: October 26, 2026

tert-butyl (2R)-2-hydroxypropanoate → tert-butyl (2S)-2-[4-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoate

https://huagongshe.com/reaction/16077

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl (2R)-2-hydroxypropanoateHCID 10953655—
Reactant4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenolHCID 67277061—
Producttert-butyl (2S)-2-[4-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propanoateHCID 67276583—

Reaction Steps

The subtitle compound was prepared by the method of Example 2 step a) using the product from step e) and tert-butyl (R)-(+) lactate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07737135B2
Source datasetuspto-grants-2010_06
ORD IDord-a37936cdbea845e78e095808545a213f
Source noteuspto-grants-2010_06