epsilon-CAPROLACTONE → HCID 86743370, compound

Participants

Reaction Conditions

Reaction Steps

About 144 g (1.0 g) of N-(3-aminopropyl) morpholine was mixed with 144 g (1.0 mole) of E-caprolactone in the presence of 0.1 of stannous octanoate and heated slowly to 140° C. under nitrogen atmosphere while stirring. The course of the reaction was observed by the disappearance of caprolactone by infrared analysis. At the end of the first hour at 140° C., the infrared spectrum showed complete conversion at the lactone to the corresponding hydroxyl terminated amide. The resulting adduct analyzed for 10.3% of N and a hydroxyl number of 114.7.

Provenance & Evidence