HCID 23047191, compound → propan-2-yl 6-chlorohexanoate

Participants

Reaction Steps

A solution of 10.5 gm(0.03 mol) of diamine 15, 6.2 gm(0.03 mol) of isopropyl 5-chlorohexanoate, and 10.0 gm of MeOH was charged to the flask and heated to reflux. After 90 hours, 1.0 gm(5 mmol) of isopropyl 3-chlorohexanoate was added to the mixture. At least 5% amine was present after refluxing 6 hours and the heating was stopped. The crude product was removed of volatiles by rotary evaporation and washed until all of the residue was removed leaving 15 gm(94%) of Quat 7.

Provenance & Evidence