(1-Acetoxy-2,2-dichloro-3,3,3-trifluoropropyl)-2,3-dichlorobenzene → (2-Chloro-3,3,3-trifluoropropen-1-yl)-2,3-dichlorobenzene

Participants

Reaction Conditions

Reaction Steps

A solution of 59.0 g of (1-acetoxy-2,2-dichloro-3,3,3-trifluoropropyl)-2,3-dichlorobenzene in 350 ml of acetic acid is heated to 40° C., and 13.0 g of zinc powder are added portionwise. To effect completion of the reaction, the reaction mixture is heated at 90° C. for 3 hours. In further processing, thereaction mixture is taken up in ice-water, and extracted with ether. The combined organic phases are washed with water, sodium hydrogen carbonate solution and sodium chloride solution; they are then dried over magnesium sulfate, and concentrated by evaporation to thus obtain (2-chloro-3,3,3-trifluoropropen-1-yl)-2,3-dichlorobenzene in the form of yellow oil (compound No. 4.10).

Provenance & Evidence