Dimethyl Sulfoxide → 1-Bromo-4,5-difluoro-2-(trifluoromethoxy)benzene

HRID 160810Notes

Reaction equation

HRID 160810 reaction equation
[Br:1][c:2]1[c:3]([OH:10])[cH:4][c:5]([F:9])[c:6]([F:8])[cH:7]1.[CH3:18][S:19]([CH3:20])=[O:21].[F:11][C:12]([CH2:13][I:14])([F:15])[F:16].[OH2:17]>>[Br:1][c:2]1[c:3]([O:10][C:12]([F:11])([F:15])[F:16])[cH:4][c:5]([F:9])[c:6]([F:8])[cH:7]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 677091,1,1-Trifluoro-2-iodoethaneHCID 27362882-Bromo-4,5-difluorophenol

Product 1

HCID 598424311-Bromo-4,5-difluoro-2-(trifluoromethoxy)benzene

Sources & evidence

ORD record
ord-ae51e3043d2442b492607fbde23b5467
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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