Hydrazinecarboxylic acid, ethyl ester → HCID 54422165, compound

HRID 1608177Notes

Reaction equation

HRID 1608177 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]=O)=[CH:3][CH:2]=1.[CH2:13]([O:15][C:16](=[O:19])[NH:17][NH2:18])[CH3:14]>C(O)C>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]=[N:18][NH:17][C:16]([O:15][CH2:13][CH3:14])=[O:19])=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 780724-Quinolinecarboxaldehyde

Product 1

HCID 54422165HCID 54422165, compoundYield 53%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 4.72 gm (0.03 mole) of 4-quinolinecarboxaldehyde, 3.12 gm (0.03 mole) of ethylcarbazate and 100 ml of absolute ethanol is refluxed 9 hr. The solvent is evaporated. The solid is crystallized from ethyl acetate/Skellysolve B to give 3.82 gm (53%) of the title compound having a melting point of 161.2° C.

Workup

  1. temperatureis refluxed 9 hr
  2. customThe solvent is evaporated
  3. customThe solid is crystallized from ethyl acetate/Skellysolve B

Sources & evidence

ORD record
ord-ec5d118aebaa4b6988aa74d9407d0b4b
Source dataset
uspto-grants-1989_09
Patent number
US04870082

Reaction notes

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