Methanol → HCID 13657591, compound

Participants

Reaction Steps

A solution of 14.8 g=50 mmol of 1-bromo-3-chloropropyl4-chlorophenyl ketone in 30 ml of acetonitrile was added dropwise at room temperature with stirring to a suspension of 17.2 g=125 mmol of powdered potassium carbonate and 6.4 g=50 mmol of p-chlorophenol in 60 ml of acetonitrile. The mixture was stirred for 5 hours at room temperature, 0.4 g of tetrabutylammonium bromide was added, and the mixture was refluxed for 10 hours and worked up as specified in Example 1, and 12.6 g (82% of theory) of melting point: 69°-71° C. (from methanol) were obtained.

Provenance & Evidence