Imidazole → HCID 13657565, compound

HRID 1608244Notes

Reaction equation

HRID 1608244 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([C:11]3([O:14][C:15]4[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=4)[CH2:13][CH2:12]3)[CH2:10][O:9]2)=[CH:4][CH:3]=1.[NH:22]1[CH:26]=[CH:25][N:24]=[CH:23]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:11]2([O:14][C:15]3[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=3)[CH2:12][CH2:13]2)([OH:9])[CH2:10][N:22]2[CH:26]=[CH:25][N:24]=[CH:23]2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 14154687HCID 14154687, compound

Product 1

HCID 13657565HCID 13657565, compound

Procedure

3.2 g=10 mmol of 2-(4-chlorophenyl)-2-[1-(4-chlorophenoxy)cyclopropan-1-yl]-oxirane (compound from Example 14) were reacted with 2.04 g=30 mmol of imidazol, as specified in Example 2a), in the absence of a solvent, and 2.9 g (75% of theory) of melting point: 172°-173° C. were obtained.

Workup

  1. customwere obtained

Sources & evidence

ORD record
ord-4376973601124bb4b49ec8dc729f1994
Source dataset
uspto-grants-1989_09
Patent number
US04870088

Reaction notes

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