2-Chloro-3-methyl-5-nitropyridine → HCID 14626962, compound

HRID 1608251Notes

Reaction equation

HRID 1608251 reaction equation
[F:1][C:2]([F:20])([C:16]([F:19])([F:18])[F:17])[C:3]([C:5]1[CH:6]=[CH:7][C:8]2[O:12][C:11]([CH3:14])([CH3:13])[CH2:10][C:9]=2[CH:15]=1)=[O:4].Cl[C:22]1[C:27]([CH3:28])=[CH:26][C:25]([N+:29]([O-])=O)=[CH:24][N:23]=1>>[NH2:29][C:25]1[CH:26]=[C:27]([CH3:28])[C:22]([O:4][CH:3]([C:5]2[CH:6]=[CH:7][C:8]3[O:12][C:11]([CH3:14])([CH3:13])[CH2:10][C:9]=3[CH:15]=2)[C:2]([F:1])([F:20])[C:16]([F:18])([F:17])[F:19])=[N:23][CH:24]=1

Participants

3

Reactant 2

HCID 896482-Chloro-3-methyl-5-nitropyridineHCID 20061500HCID 20061500, compound

Product 1

HCID 14626962HCID 14626962, compound

Procedure

5-Amino-3-methyl-2-[1-(2,3-dihydro-2,2-dimethylbenzofuran-5-yl)-2,2,3,3,3-pentafluoropropoxy]pyridine was prepared from 2,2,3,3,3-pentafluoro-1-(2,3-dihydro-2,2-dimethylbenzofuran-5-yl)propan-1-one, by the method of Example 42. 2-Chloro-3-methyl-5-nitropyridine was used in place of 2-chloro-5-nitropyridine.

Sources & evidence

ORD record
ord-bcfcab382e2f442b93cd3ada61b7a136
Source dataset
uspto-grants-1989_09
Patent number
US04870089

Reaction notes

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