HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Pyrrolidineethanamine → 4,5-Diphenyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrazole-1-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Pyrrolidineethanamine | HCID 1344 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-(1H-pyrazol-1-yl)acetamide | HCID 14028978 | — |
| Reactant | 4,5-Diphenyl-1-(ethoxycarbonylmethyl)-pyrazole | HCID 14699551 | — |
| Product | 4,5-Diphenyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrazole-1-acetamide | HCID 14699581 | — |
Reaction Steps
By a procedure substantially similar to that of Example 18, 6.67 g of 4,5-diphenyl-N-2-(1-pyrrolidinyl)ethyl-]1H-pyrazole-1-acetamide, mp 80°-84° C., was prepared from 15 g (0.049 mol) of ethyl 4,5-diphenyl-1H-pyrazole-1-acetate of Example 1, 9 mL (0.072 mol) of N-(2-aminoethyl)pyrrolidine and 62 mL (0.36 mol) of diisopropylethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04870095 |
| Source dataset | uspto-grants-1989_09 |
| ORD ID | ord-26dfcc05106443b28ed4a3ba57078c6b |
| Source note | uspto-grants-1989_09 |