N-Methylcyclohexylamine → HCID 54103042, compound

HRID 1608326Notes

Reaction equation

HRID 1608326 reaction equation
[CH2:1]([C:3]1[C:4](=[O:21])[NH:5][C:6]2[C:11]([N:12]=1)=[CH:10][C:9]([O:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([OH:20])=O)=[CH:8][CH:7]=2)[CH3:2].CC1[C:24](=O)[NH:25][C:26]2[C:31](N=1)=[CH:30][C:29](OCCCCC(O)=O)=[CH:28][CH:27]=2.CNC1CCCCC1.C(NC1CCCCC1)C>>[CH2:1]([C:3]1[C:4](=[O:21])[NH:5][C:6]2[C:11]([N:12]=1)=[CH:10][C:9]([O:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([N:25]([CH:26]1[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1)[CH3:24])=[O:20])=[CH:8][CH:7]=2)[CH3:2]

Participants

5

Reactant 4

HCID 7514N-MethylcyclohexylamineHCID 21609N-Ethyl cyclohexylamineHCID 19849129HCID 19849129, compoundHCID 19849132HCID 19849132, compound

Product 1

HCID 54103042HCID 54103042, compoundYield 77.4%

Procedure

In Example 72 the compound 1013 was replaced by compound 1037 and N-methylcyclohexylamine was replaced by N-ethylcyclohexylamine 0.77 ml to obtain the compound 1035.

Sources & evidence

ORD record
ord-7f48b883f51843fe8499977744b54561
Source dataset
uspto-grants-1989_09
Patent number
US04870175

Reaction notes

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