Hydrochloric Acid → HCID 14618953, compound

Participants

Reaction Conditions

Reaction Steps

The 1-iodo-2-(m-phenoxyphenoxy)-1,1,2,2-tetrafluoroethane (2.06 g, 5 mmoles) is then mixed with iodobenzene (1.12 g, 5.5 mmoles), activated copper (0.7 g, 11 mmoles) and 20 ml dimethyl sulfoxide (DMSO) and heated to 120° C. The mixture is heated and stirred at 120° C. for 16 hours and then cooled, diluted with 100 ml water, acidified with HCl and the product is extracted with ethyl acetate (2×40 ml). A colorless oil, 1-(m-phenoxyphenoxy)-2-phenyl-1,1,2,2-tetrafluoroethane, is recovered in a yield of 69 percent based on 1-iodo-2-(m-phenoxyphenoxy)-1,1,2,2-tetrafluoroethane (1.3 g). The identity of the product is confirmed by mass spectrometry. The 1-(m-phenoxyphenoxy)-2-phenyl-1,1,2,2-tetrafluoroethane has a pour point of -23° C.

Provenance & Evidence