HCID 14877939, compound → HCID 19983596, compound

HRID 1608400Notes

Reaction equation

HRID 1608400 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:26]2[CH:31]=[CH:30][C:29]([F:32])=[CH:28][CH:27]=2)=[C:9]([N:15]2[C:19]([C:20]3C=CC=CC=3)=[N:18][N:17]=[N:16]2)[C:10](OCC)=[O:11])=[CH:4][CH:3]=1.FC1C=CC(C(C2C=CC(F)=CC=2)=C(N2C(C)=NN=N2)C(OCC)=O)=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:26]2[CH:27]=[CH:28][C:29]([F:32])=[CH:30][CH:31]=2)=[C:9]([N:15]2[C:19]([CH3:20])=[N:18][N:17]=[N:16]2)[CH2:10][OH:11])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 14877939HCID 14877939, compoundHCID 14877940HCID 14877940, compound

Product 1

HCID 19983596HCID 19983596, compound

Procedure

The general procedure of Example 5 was repeated, except that the ethyl 3,3-bis(4-fluorophenyl)-2-(5-phenyl-1H-tetrazol-1-yl)-2-propenoate utilized therein was replaced by 4.87 g of ethyl 3,3-bis(4-fluorophenyl)-2-(5-methyl-1H-tetrazol-1-yl)-2-propenoate [prepared in Example 14] and there was thereby produced 4.45 g of the title compound which was used in the next step without further purification.

Sources & evidence

ORD record
ord-0d43c78708944311ae2085b0ad5e29db
Source dataset
uspto-grants-1989_09
Patent number
US04870187

Reaction notes

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