HCID 14877941, compound → HCID 14877943, compound

HRID 1608401Notes

Reaction equation

HRID 1608401 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:23]2[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=2)=[C:9]([N:12]2[C:16]([C:17]3C=CC=CC=3)=[N:15][N:14]=[N:13]2)[CH2:10][OH:11])=[CH:4][CH:3]=1.FC1C=CC(C(C2C=CC(F)=CC=2)=C(N2C(C)=NN=N2)CO)=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:23]2[CH:24]=[CH:25][C:26]([F:29])=[CH:27][CH:28]=2)=[C:9]([N:12]2[C:16]([CH3:17])=[N:15][N:14]=[N:13]2)[CH:10]=[O:11])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 14877941HCID 14877941, compoundHCID 19983596HCID 19983596, compound

Product 1

HCID 14877943HCID 14877943, compound

Procedure

The general procedure of Example 6 was repeated, except that the 3,3-bis(4-fluorophenyl)-2-(5-phenyl-1H-tetrazol-1-yl)-2-propenol utilized therein was replaced by 4.45 g of 3,3-bis(4-fluorophenyl)-2-(5-methyl-1H-tetrazol-1-yl)-2-propenol [prepared in Example 15] and there was thereby produced 3.76 g of the title compound which was used in the next step without further purification.

Sources & evidence

ORD record
ord-70a9503d1e3b4502a0684b87dce69d45
Source dataset
uspto-grants-1989_09
Patent number
US04870187

Reaction notes

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