Borane;tetrahydrofuran → HCID 178419202, compound

Participants

Reaction Steps

To N,N-dimethyl-3-hydroxytricyclo-[3.3.1.13,7 ]decan-1-amine (1.3 g; 0.0067 mole) dissolved in THF, under N2 and chilled in ice, is added borane-THF (14 ml; 0.014 mole) over 5 min. The ice bath is removed after an additional 5 min. and stirred at room temperature for 3 hrs. To this mixture is added ether (100 ml), washed with saturated NaHCO3 and evaporated to dryness to give borane N,N-dimethyl-3-hydroxytricyclo[3.3.1.13,7 ]decan-1-amine complex which is used directly in Step C.

Provenance & Evidence