HCID 15207570, compound → HCID 20086983, compound

HRID 1608649Notes

Reaction equation

HRID 1608649 reaction equation
[Cl:1][C:2]1[CH:7]=[N:6][N:5]([CH3:8])[C:4](=[O:9])[C:3]=1[NH:10][CH2:11][CH2:12][CH2:13]Cl.[CH3:15][O:16][C:17]1[CH:18]=[C:19](NCC)[CH:20]=[C:21]([O:25][CH3:26])[C:22]=1[O:23][CH3:24]>>[Cl:1][C:2]1[CH:7]=[N:6][N:5]([CH3:8])[C:4](=[O:9])[C:3]=1[NH:10][CH2:11][CH2:12][CH2:13][N:5]([CH2:4][CH2:3][C:19]1[CH:20]=[C:21]([O:25][CH3:26])[C:22]([O:23][CH3:24])=[C:17]([O:16][CH3:15])[CH:18]=1)[CH3:8]

Participants

3

Reactant 2

HCID 15207570HCID 15207570, compoundHCID 20086988HCID 20086988, compound

Product 1

HCID 20086983HCID 20086983, compoundYield 34%

Procedure

On starting from 5-chloro-4-(3-chloropropylamino)-2-methyl-3(2H)-pyridazinone and 3,4,5-trimethoxyphenyl ethyl amine and proceeding according to method c) with the difference that melting is carried out at 140° C. for 2.5 hours the desired compound is obtained with a yield of 34%. Rf =0.6.

Sources & evidence

ORD record
ord-14c38def6eea4ca8a0ce1737496e9ff3
Source dataset
uspto-grants-1995_03
Patent number
US05395934

Reaction notes

Loading…