Hydrochloric Acid → Binol

Participants

Reaction Steps

5 ml of methanol and. 50 ml of 0.1M hydrochloric acid were added under ice cooling to 2.55 g (4.58 mmol) of (R)-(+)-2,2'-dihydroxy-1,1'-binaphthyl-(1R,2R)-(-)1,2-cyclohexanediamine.benzene (1:1:2) complex obtained in the same manner as in Example 5, followed by stirring for 30 minutes. The precipitated white solid was washed with water, and then dried under reduced pressure to obtain 1.29 g (4.51 mmol) of (R)-(+)-2,2'-dihydroxy-1,1'-binaphthyl. Yield =98%, optical purity=81%, m.p.=202°-203° C., and [α]D24 =+29.7° (c 0.539, THF).

Provenance & Evidence