3-(Trifluoromethyl)benzenesulfonyl chloride → HCID 20085682, compound

Participants

Reaction Steps

The titled compound was prepared substantially in accordance with the method set forth in Example 1C using 4.84 g (0.0198 mol) of 2-amino-N-[2-(1-methyl-1H-imidazol-2-yl)ethyl]benzamide (prepared in a similar manner as the compound in Example 6A) and 5.25 g (0.0215 mol) of m-trifluoromethylbenzenesulfonyl chloride. After reducing the organic layer to dryness, the resulting yellow solid was recrystallized from an ethyl acetate/diethyl ether solution to provide 7.8 g of the desired titled compound (m.p. 127°-129° C.)

Provenance & Evidence