HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 4-[2-(Pyridin-2-yl)ethenyl]benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Methylpyridine | HCID 7975 | — |
| Reactant | 4-Cyanobenzaldehyde | HCID 66042 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 4-[2-(Pyridin-2-yl)ethenyl]benzonitrile | HCID 54476743 | 46% |
Reaction Steps
A mixture of 20.4 g (0.2 mol) acetic acid anhydride, 18.6 g (0.2 mol) 2-methylpyridine and 26.2 g (0.2 mol) 4-cyanobenzaldehyde is heated to reflux for 24 h. One allows to cool, mixes with excess ether and filters. One isolates 18.8 g of title compound (46% of theory) of the m.p. 98°-98° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05399575 |
| Source dataset | uspto-grants-1995_03 |
| ORD ID | ord-af7dd83a9f78453fbf7a21fd7f3a6ed5 |
| Source note | uspto-grants-1995_03 |