Hydrochloric Acid → HCID 20083135, compound

Participants

Reaction Steps

To 370 mg (1.3 mmol) of the compound (145) obtained in Example 30, 2 ml of concentrated hydrochloric acid and 10 ml of acetic acid were added, and the solution was heated at reflux for 2 hours. The solvent was removed by distillation. Crystals were dispersed in ethanol and filtered and washed with ethanol and ether in this order to obtain 270 mg of the subject compound (146) in a 77% yield.

Provenance & Evidence