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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 16091Generated: October 25, 2026

2-Methylpyrrolidine → 1-[(3,5'-Dichloro-2'-methoxy[1,1'-biphenyl]-4-yl)carbonyl]-2-methyl-pyrrolidine

https://huagongshe.com/reaction/16091

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethylpyrrolidineHCID 13003—
Reactant[[3',5-dichloro-4'-[[(2R,6S)-2,6-dimethyl-1-piperidinyl]carbonyl][1,1'-biphenyl]-2-yl]oxy]-acetic acidHCID 11517726—
Product1-[(3,5'-Dichloro-2'-methoxy[1,1'-biphenyl]-4-yl)carbonyl]-2-methyl-pyrrolidineHCID 68604062—

Reaction Steps

The sub-title compound was prepared by the method of example 18 step a) using the product of step example 21 step a) and 2-methylpyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07737135B2
Source datasetuspto-grants-2010_06
ORD IDord-f89d528f07aa40eab0876808d4b23adb
Source noteuspto-grants-2010_06