HCID 19698635, compound → HCID 54345234, compound

HRID 1609112Notes

Reaction equation

HRID 1609112 reaction equation
[Cl:1][C:2]1[CH:15]=[CH:14][C:13]2[C@@H:12]3[CH2:16][C@H:5]([C:6]4[C:11]3=[CH:10][CH:9]=[CH:8][CH:7]=4)[C:4]=2[C:3]=1[C:17](O)=O.[CH3:20][N:21]([CH3:40])[S:22]([C:25]1[CH:30]=[CH:29][C:28]([O:31][CH3:32])=[CH:27][C:26]=1[CH2:33][CH:34]1[CH2:39][CH2:38][NH:37][CH2:36][CH2:35]1)(=[O:24])=[O:23]>>[Cl:1][C:2]1[CH:15]=[CH:14][C:13]2[C@@H:12]3[CH2:16][C@@:5]([CH2:4][N:37]4[CH2:38][CH2:39][CH:34]([CH2:33][C:26]5[CH:27]=[C:28]([O:31][CH3:32])[CH:29]=[CH:30][C:25]=5[S:22](=[O:24])(=[O:23])[N:21]([CH3:20])[CH3:40])[CH2:35][CH2:36]4)([C:6]4[C:11]3=[CH:10][CH:9]=[CH:8][CH:7]=4)[C:17]=2[CH:3]=1

Participants

3

Reactant 2

HCID 19698635HCID 19698635, compoundHCID 54396660HCID 54396660, compound

Product 1

HCID 54345234HCID 54345234, compound

Procedure

Using a procedure similar to that described in Example 55a, except starting with (9R,10R)-2-chloro-9,10-dihydro-9,10-methanoanthracenecarboxylic acid, prepared as described in Example 2a, and 4-(2-dimethylsulfamoyl-5-methoxyphenylmethyl) piperidine, prepared as described in Example 58e, the title compound was obtained as a white solid (617 mg, 1.09 mmol, 57%)

Workup

  1. customprepared
  2. customprepared

Sources & evidence

ORD record
ord-76fd0202b58344bc9fa3705fb8ce3c59
Source dataset
uspto-grants-1995_03
Patent number
US05399568

Reaction notes

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