Boron tribromide → 4-Hydroxyphenyl cycloheptyl ketone

HRID 1609232Notes

Reaction equation

HRID 1609232 reaction equation
[CH:1]1([C:8]([C:10]2[CH:15]=[CH:14][C:13]([O:16]C)=[CH:12][CH:11]=2)=[O:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.B(Br)(Br)Br>ClCCl>[CH:1]1([C:8]([C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 20084233HCID 20084233, compound

Product 1

HCID 200842354-Hydroxyphenyl cycloheptyl ketone

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound is prepared in analogy to the procedure of Example II from 53.2 g (0.229 mol) of the compound from Example XI and 458 ml of a 1M solution of boron tribromide (0.458 mol) in dichloromethane.

Sources & evidence

ORD record
ord-015ef0ed24044b0c80b1513e939965ee
Source dataset
uspto-grants-1995_03
Patent number
US05399698

Reaction notes

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