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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1609233Generated: October 30, 2026

Potassium Carbonate → 4-(Quinolin-2-yl-methoxy)phenyl cycloheptyl ketone

https://huagongshe.com/reaction/1609233

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2-(Chloromethyl)quinoline hydrochlorideHCID 3083823—
Reactant4-Hydroxyphenyl cycloheptyl ketoneHCID 20084235—
Product4-(Quinolin-2-yl-methoxy)phenyl cycloheptyl ketoneHCID 20084238—

Reaction Steps

In analogy to the procedure of Example III, the title compound is prepared from 10 g (45.8 mmol) of the compound from Example XII, 10.3 g (48.1 mmol) of 2-chloromethylquinoline hydrochloride and 13.8 g (0.10 mol) of potassium carbonate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05399698
Source datasetuspto-grants-1995_03
ORD IDord-211c2253a5914f6b891ba5bf1e7cd068
Source noteuspto-grants-1995_03