HCID 11197435, compound → HCID 20084430, compound

Participants

Reaction Steps

In 130 ml of ethanol was suspended 22.5 g of ethyl 2-(2-nitrophenylthio)benzoate and, then, a solution of 58.7 g of tin(IV) chloride dihydrate in a mixture of 70 ml of concentrated hydrochloric acid and 45 ml of ethanol was added en bloc. The mixture was stirred at room temperature for 3 hours, after which it was poured in a mixture of 600 ml of 10% aqueous sodium hydroxide solution and 500 ml of ether with cooling and stirring. The ether layer was separated, washed with water and saturated aqueous sodium chloride solution in that order and dried. Finally, the ether was distilled off to give 20.5 g of the title compound as a light yellow oil.

Provenance & Evidence