Hydrochloric Acid → HCID 178444958, compound

Participants

Reaction Steps

In 15 ml of N,N-dimethylformamide (DMF) was dissolved 1.5 g of N-[2-(3-cyanomethoxyphenoxy)phenyl]-4-hexyloxybenzamide followed by addition of 0.44 g of sodium azide and 0.37 g of ammonium chloride, and the mixture was stirred at 105°-110° C. for 1 hour. After cooling, the reaction mixture was diluted with ice-water and acidified with hydrochloric acid. The resulting precipitate was collected by filtration and recrystallized from ethanol to give 1.35 g of the title compound as white crystals, m.p. 158°-159° C.

Provenance & Evidence