Hydrochloric Acid → HCID 178521995, compound

Participants

Reaction Steps

In 20 ml of DMF were dissolved 1.35 g of N-[2-(2-cyanophenylthio)phenyl]-4-(4-phenylbutoxy)benzamide, 0.55 g of sodium azide and 0.46 g of ammonium chloride, and the mixture was stirred at 110°-115° C. for 5 hours. Then, 0.18 g of sodium azide and 0.15 g of ammonium chloride were further added and the mixture was stirred at 110° to 115° C. for 2 hours. After addition of ice-water, the reaction mixture was neutralized with diluted hydrochloric acid and the precipitate was collected by filtration and recrystallized from ethanol to give 0.95 g of the title compound, m.p. 156°-159° C.

Provenance & Evidence