Hydrochloric Acid → HCID 178444961, compound

Participants

Reaction Conditions

Reaction Steps

In 20 ml of DMF was dissolved 1.20 g of N-[2-(2-cyanophenylthio)phenyl]-4-hexyloxybenzamide followed by addition of 0.36 g of sodium azide and 0.30 g of ammonium chloride, and the mixture was stirred at 120° C. for 3 hours. Then, the same amounts of sodium azide and ammonium chloride as above were added twice at an interval of 3 hours. The reaction mixture was then acidified with diluted hydrochloric acid and the resulting crystals were collected by filtration and washed with water. The crystals were dissolved in chloroform and dried over magnesium sulfate and the solvent was distilled off. The crystals thus obtained were recrystallized from ethyl acetate-n-hexane to give 1.1 g of the title compound as white crystals, m.p. 154°-156° C.

Provenance & Evidence