HRID1609313

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12801

Homophthalic acid anhydride

C9H6O3

HCID15136084

未命名化合物

PRODUCTS

生成物

结构：O=C(Cc1ccccc1C(=O)O)Nc1cccc(/C=C/c2nc(C3CCCCC3)cs2)c1

HCID20084320

未命名化合物

收率 93.7%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

A solution of 2.8 g of (E)-3-[2-[4-(cyclohexyl)-2-thiazolyl]ethenyl]benzeneamine, 1.78 g of homophthalic anhydride and 30 ml of toluene were heated to reflux for 0.5 hr. Cooling and filtration yielded 4.12 g of (E)-2-[2-[3-[2-[4-(cyclohexyl)-2-thiazolyl]ethenyl]phenylamino]-2-oxoethyl]benzoic acid; m.p. 210°-211° C. from tetrahydrofuran.

WORKUP

后处理

temperatureto reflux for 0.5 hr
temperatureCooling
filtrationfiltration