反应详情

175.3 g of sodium sulfoethylisothiocyanate was added to a solution obtained by adding 600 ml of methyl alcohol and 300 ml of water to 114.2 g of 1-acetyl-1-methylhydrazine. The system was then heated under reflux for 4 hours. After the reaction, the reaction solution was dried under reduced pressure. The resulting solid matter was then recrystallized from 1 l of methyl alcohol to obtain 169.4 g (yield: 66.0%) of the desired compound. m.p. 255°-256° C.

1. customobtained
2. temperatureThe system was then heated
3. temperatureunder reflux for 4 hours
4. customAfter the reaction
5. customthe reaction solution was dried under reduced pressure
6. customThe resulting solid matter was then recrystallized from 1 l of methyl alcohol