Phenyl isocyanate → HCID 15107596, compound

Participants

Reaction Steps

A mixture of 1.19 g of phenyl isocyanate, 3.67 g of 2-[(2S,3S)-3-amino-4-cyclohexyl-2-hydroxybutyl ]-2-methyl- 1,3-dithiane 1,1,3,3-tetroxide, 1.01 g of triethylamine and 60 ml of dichloromethane is stirred at 20° for 5 h. The usual working up gives 2-[(2S,3S)-4-cyclohexyl-2-hydroxy-3-(N'-phenylureido)-butyl]-2-methyl-1,3-dithiane 1,1,3,3-tetroxide, m.p 238°-240°, FAB 487.

Provenance & Evidence