HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamide → 8-Methylquinazolin-4(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | 2-Amino-3-methylbenzoic acid | HCID 78101 | — |
| Product | 8-Methylquinazolin-4(1H)-one | HCID 135471300 | — |
Reaction Steps
2-Amino-3-methylbenzoic acid (1.00 g, 0.0066 mol) and formamide (12 mL) were heated together at 130° C. for 20 hr. under nitrogen. After cooling to room temperature, the solid was filtered off, washed with diethyl ether and dried in vacuo to leave 8-methylquinazolin-4(3H)-one (1.19 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05401745 |
| Source dataset | uspto-grants-1995_03 |
| ORD ID | ord-39b936ef7385494989d22440ecae9045 |
| Source note | uspto-grants-1995_03 |