3-(Chloromethyl)pyridine hydrochloride → 7-Bromo-2-pyridin-3-ylmethyl-2H-phthalazin-1-one

HRID 1609600Notes

Reaction equation

HRID 1609600 reaction equation
[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[N:7][NH:8][C:9]2=[O:12])=[CH:4][CH:3]=1.Cl.Cl[CH2:15][C:16]1[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=1>>[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[N:7][N:8]([CH2:15][C:16]3[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=3)[C:9]2=[O:12])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 233943-(Chloromethyl)pyridine hydrochlorideHCID 222653177-bromo-2H-phthalazin-1-one

Product 1

HCID 544303767-Bromo-2-pyridin-3-ylmethyl-2H-phthalazin-1-one

Procedure

The titled compound was prepared from 7-bromo-1 (2H)-phthalazinone and 3-chloromethylpyridine hydrochloride in the same manner as in Example 10 (1) a).

Sources & evidence

ORD record
ord-1d6077715b0f46e3b664ef594bcac4f8
Source dataset
uspto-grants-1995_03
Patent number
US05401756

Reaction notes

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