HRID1609692

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6322

未命名化合物

$结构：CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(C[N+]3(C)CCCC3)CS[C@H]12)c1csc(N)n1.Cl.O.O.[Cl-]$

HCID5491422

未命名化合物

PRODUCTS

生成物

$结构：CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(C[N+]3(C)CCCC3)CS[C@H]12)c1csc(N)n1.Cl.NC(N)=NCCC[C@H](N)C(=O)O.O.O.[Cl-]$

HCID178502815

未命名化合物

PROCEDURE

实验过程

Stable cefepime dihydrochloride dihydrate, 150 grams, and L(+) arginine, 86.25 g, were weighed and placed in a V-blender. The mixture was blended for 32 minutes. The blend was then screened through a 40 mesh US standard sieve, returned to the blender and blended for another 32 minutes.

WORKUP

后处理

waitblended for another 32 minutes

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-327276feb463425788e193fae26bbce7
来源数据集: uspto-grants-1995_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05401842
来源说明: uspto-grants-1995_03

反应 SMILES

[CH3:1][N+:2]1([CH2:7][C:8]2[CH2:29][S:28][C@@H:11]3[C@H:12]([NH:15][C:16](/[C:18](/[C:22]4[N:26]=[C:25]([NH2:27])[S:24][CH:23]=4)=[N:19]\[O:20][CH3:21])=[O:17])[C:13](=[O:14])[N:10]3[C:9]=2[C:30]([OH:32])=[O:31])[CH2:6][CH2:5][CH2:4][CH2:3]1.[OH2:33].O.[ClH:35].[Cl-].[CH2:37]([CH2:44][N:45]=[C:46]([NH2:48])[NH2:47])[CH2:38][C@H:39]([NH2:43])[C:40]([OH:42])=[O:41]>>[CH3:1][N+:2]1([CH2:7][C:8]2[CH2:29][S:28][C@@H:11]3[C@H:12]([NH:15][C:16](/[C:18](/[C:22]4[N:26]=[C:25]([NH2:27])[S:24][CH:23]=4)=[N:19]\[O:20][CH3:21])=[O:17])[C:13](=[O:14])[N:10]3[C:9]=2[C:30]([OH:32])=[O:31])[CH2:3][CH2:4][CH2:5][CH2:6]1.[OH2:41].[OH2:33].[ClH:35].[Cl-:35].[CH2:37]([CH2:44][N:45]=[C:46]([NH2:48])[NH2:47])[CH2:38][C@H:39]([NH2:43])[C:40]([OH:42])=[O:41]