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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1609774Generated: October 31, 2026

Phenol → Benzyl Phenyl Ether

https://huagongshe.com/reaction/1609774

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenolHCID 996—
ReactantDimethylformamideHCID 6228—
ReactantSodium amideHCID 24533—
ReactantSodium hydrideHCID 24758—
ReactantSodiumHCID 5360545—
ReactantBarium Oxide Nanoparticle DispersionHCID 9855530—
CatalystSilver(II) oxideHCID 92152—
SolventDimethyl SulfoxideHCID 679—
SolventDiethyl EtherHCID 3283—
SolventTetrahydrofuranHCID 8028—
SolventTriethylamineHCID 8471—
ProductBenzyl Phenyl EtherHCID 70352—

Reaction Steps

In Scheme 3, the starting phenol is reacted with a benzyl halide in the presence of a base (e.g. sodium amide, triethylamine, sodium hydroxyde, barium oxide, silver oxide, sodium hydride) in an inert solvent (e.g. ether, dimethylsulfoxide, dimethylformamide, tetrahydrofuran) to give a benzyl phenyl ether, which is an example of the derivative of the alkoxyiminocarboxylic acid (V).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05401877
Source datasetuspto-grants-1995_03
ORD IDord-213991a8aea3483ba2adaa487c52d82c
Source noteuspto-grants-1995_03