HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl (morpholin-4-ylcarbonothioyl)carbamate → {[1-(4-Cyano-1-propyl-piperidin-4-ylcarbamoyl)-3,3-dimethyl-butylimino]-morpholin-4-yl-methyl}-carbamic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl (morpholin-4-ylcarbonothioyl)carbamate | HCID 2824559 | — |
| Reactant | 2-Amino-4,4-dimethyl-pentanoic acid(4-cyano-1-propyl-piperidin-4-yl)amide bis hydrochloride salt | HCID 86585201 | — |
| Product | {[1-(4-Cyano-1-propyl-piperidin-4-ylcarbamoyl)-3,3-dimethyl-butylimino]-morpholin-4-yl-methyl}-carbamic acid ethyl ester | HCID 22091417 | — |
Reaction Steps
The title compound was prepared starting from (Morpholine-4-carbothioyl)-carbamic acid ethyl ester and 2-amino-4,4-dimethyl-pentanoic acid (4-cyano-1-propyl-piperidin-4-yl)amide bis hydrochloride salt according to the procedure from Example 76. MS, m/z 460=M+1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06982272B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-b9ff15f1dbca4324a994762e0ae79b23 |
| Source note | uspto-grants-2006_01 |