HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 17747748, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 22261357 | HCID 22261357 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 17747748 | HCID 17747748 | — |
Reaction Steps
Isopropyl-2-(2,4-dimethoxyphenyl)-4,5-dihydro-thiazole-4-carboxylate is reacted with 50% potassium hydroxide and excess methyl iodide in dichloromethane in the presence of O(9)-allyl-N-9-anthracenylmethylcinchonidium bromide to form isopropyl-2-(2,4-dimethoxyphenyl)-4-methyl-4,5-dihydro-thiazole-4-(S)-carboxylate in enantiomeric excess.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06982335B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-c86e6a3d1e2a42bf88ad35cba7b32fe1 |
| Source note | uspto-grants-2006_01 |