Hydrochloric Acid → HCID 22261765, compound

Participants

Reaction Steps

A mixture of ethyl 5-[(acetoxy)methyl]-4-(4-fluorophenyl)-2-phenylfuran-3-carboxylate (4.020 g, 10.51 mmol) and a solution (50 ml) of 10% hydrogen chloride in methanol was stirred at room temperature for 2.5 days. The solvent of the reaction solution was evaporated under reduced pressure and the obtained crude product was purified by silica gel column chromatography (hexane/ethyl acetate=9/1) to give the objective substance.

Provenance & Evidence