6-Methylimidazo[2,1-B][1,3]thiazole-5-carboxylic acid → Tert-butyl 2-[[(6-methylimidazo[2,1-b][1,3]thiazole-5-carbonyl)amino]methyl]-3-azabicyclo[3.1.0]hexane-3-carboxylate

HRID 161029Notes

Reaction equation

HRID 161029 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][NH2:15])[CH:10]2[CH2:11][CH:12]2[CH2:13]1.[CH3:16][c:17]1[n:18][c:19]2[s:20][cH:21][cH:22][n:23]2[c:24]1[C:25](=[O:26])[OH:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][NH:15][C:25]([c:24]2[c:17]([CH3:16])[n:18][c:19]3[s:20][cH:21][cH:22][n:23]32)=[O:26])[CH:10]2[CH2:11][CH:12]2[CH2:13]1

Participants

3

Reactant 2

HCID 3299796-Methylimidazo[2,1-B][1,3]thiazole-5-carboxylic acidHCID 57437194Tert-butyl 2-(aminomethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

Product 1

HCID 68445298Tert-butyl 2-[[(6-methylimidazo[2,1-b][1,3]thiazole-5-carbonyl)amino]methyl]-3-azabicyclo[3.1.0]hexane-3-carboxylate

Sources & evidence

ORD record
ord-5378e4d0b5044afabdbb26f258f5cd28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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